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GENOTOXICITY

DNA Fragmentation
Comet test

CELLULAR METABOLISM

ATP, ADP, AMP concentrations measurement
Oxygen consumption maesurement
Glycolisis level measurement

CITOTOXICITY

Neutral red, MTT
Lactate dehydrogenase activity measurement
Neo-synthesis of the macromolecules (ADN, ARN, Proteínas)
Phototoxicity (COLIPA)

PIGMENTATION

Melanin measurement
Assessment of the activity tyrosinase

ANTI-INFLAMMATORY ACTIVITY

Inflammation mediator's measurement
Cytokines (IL1-a,IL-6,...)
PGE2
Adhesion factors (ICAM 1)

Neurogenic anti-inflammatory activity
Neuropeptids measurement

COMUNICACIÓN CELULAR

Medida de conexcinas 43 (anticuerpo monoclonal)
Expresión de ARN-m (TR-PCR)




DERMAL REGENERATION

Assessment of proteoglycanes (FPLC)
Assessment of glycosaminoglycanes
Assessment of the collagens

EPIDERMAL REGENERATION

Stimulating activity of the epidermis (ki-67, filaggrine)

APOPTOSIS

Cell cycle study
Dosage of the P53
Assessment of the apoptosis (apoptag)

ANTI-RADICALAR ACTIVITY

MDA and NO measurement
Superoxide dismutase measurement
Glutathion peroxydase measurement
Glutathion reductase measurement


  
C/Caspe, 104, bjs 08013 Barcelona, Spain Tel: +34 93 246 92 18 Fax: +34 93 246 92 19